Cardiovascular Medical Devices.

Our goal is to understand the interactions of medical devices with patients’ blood, proteins and cells

with a view to developing more sophisticated and compatible materials for medical devices.

The Cardiovascular Medical Devices Group works to understand the interactions of medical devices with patients’ blood, proteins and cells to develop more sophisticated and compatible materials for medical devices for the diagnosis and treatment of cardiovascular disease.

What impact will this research have? 

Despite the widespread use of medical devices in cardiovascular medicine, including artificial hearts, vascular stents, vascular grafts, heart valves, pacemakers, catheters and cardiopulmonary bypass circuits, many side effects occur due to the materials used to make these devices, such as blood clots (thrombosis) and microbe adhesion (biofouling). Thrombosis of medical devices is currently managed with medication that causes additional complications, such as bleeding from antiplatelet or anticoagulant drugs. Biofouling is treated with antibiotics, however, antibiotics can’t always penetrate the biofilm and the overuse of antibiotics is leading to antibiotic resistant pathogens.  Increased understanding of biointerface interactions and methodology to assess materials could lead to the development of new more compatible materials and devices to reduce the use of drugs and risks for patients. 

Current projects and goals

Our team applies cutting edge bioengineering tools to develop new methodologies to assess and understand the interplay of events at the biointerface, where the devices interact with the patient, and manipulate this interplay to improve medical device function, create novel medical devices and diagnostics and both drug and non-drug based avenues for therapies. 

Research group led by:
Research covers areas of:
Latest news

Meet the team: Zohra Kakall

PhD student Zohra Kakall has always been fascinated by whole body physiology and the integration between the brain and other bodily systems. This fascination drew her to the HRI High Blood Pressure Group - which focuses on the way that brain networks control airways, breathing and blood pressure - and led her on a research trip across Europe.

Current team update

Dr Anna Waterhouse invited to speak at Joint Annual Scientific Meeting in Hobart. 

Dec 05, 2016

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